Nintedanib* in combination with docetaxel is a treatment for lung cancer patients with advanced adenocarcinoma, after first-line chemotherapy, that targets the three main receptors involved in angiogenesis and tumour growth.1
*Nintedanib is approved in the EU under the brand name Vargatef® for use in combination with docetaxel in adult patients with locally advanced, metastatic or locally recurrent NSCLC of adenocarcinoma tumour histology after first-line chemotherapy. Nintedanib is under regulatory review by health authorities in other countries outside the EU. Nintedanib is not approved in other oncology indications.
Reck M, et al. Docetaxel plus nintedanib versus docetaxel plus placebo in patients with previously treated non-small cell lung cancer (LUME-Lung1): a phase 3, double-blind, randomised controlled trial. Lancet Oncol 2014;15:143–55.